The Protective Role of 1,8-Dihydroxynaphthalene–Melanin on Conidia of the Opportunistic Human Pathogen Aspergillus fumigatus Revisited: No Role in Protection against Hydrogen Peroxide and Superoxides

Author:

Keizer E. M.12,Valdes I. D.1,McCann B. L.3,Bignell E. M.3,Wösten H. A. B.1,de Cock H.12ORCID

Affiliation:

1. Microbiology, Department of Biology, Utrecht University, Utrecht, the Netherlands

2. Institute of Biomembranes, Utrecht University, Utrecht, the Netherlands

3. MRC Centre for Medical Mycology, University of Exeter, Exerter, United Kingdom

Abstract

Opportunistic pathogens likeAspergillus fumigatushave strategies to protect themselves against reactive oxygen species like hydrogen peroxides and superoxides that are produced by immune cells. DHN-melanin is the green pigment on conidia ofAspergillus fumigatusand more than 2 decades ago was reported to protect conidia against hydrogen peroxide.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference49 articles.

1. Development in Aspergillus

2. Aspergillus fumigatus spore concentration in outside air: Cardiff and St Louis compared

3. Menacing Mold: The Molecular Biology of Aspergillus fumigatus

4. Moore D, Robson G, Trincy T. 2011. Clinical groupings for human fungal infections. 21st century guidebook to fungi. Cambridge University Press, Cambridge, United Kingdom.

5. The clinical spectrum of pulmonary aspergillosis

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3