Lactobacillus Mucosal Vaccine Vectors: Immune Responses against Bacterial and Viral Antigens-Reference-Cited by-同舟云学术

Lactobacillus Mucosal Vaccine Vectors: Immune Responses against Bacterial and Viral Antigens

Published:2018-06-27 Issue:3 Volume:3 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

LeCureux Jonathan S.¹^ORCID,Dean Gregg A.²^ORCID

Affiliation:

1. Department of Natural and Applied Sciences, Evangel University, Springfield, Missouri, USA

2. Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA

Abstract

Lactic acid bacteria (LAB) have been utilized since the 1990s for therapeutic heterologous gene expression. The ability of LAB to elicit an immune response against expressed foreign antigens has led to their exploration as potential mucosal vaccine candidates.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00061-18

Reference147 articles.

1. Food-Grade Organisms as Vaccine Biofactories and Oral Delivery Vehicles

2. Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria

3. Development of a gene delivery system in Streptococcus gordonii using thymidylate synthase as a selection marker