Culture of Clinical Specimens Reveals Extensive Diversity of Legionella pneumophila Strains in Arizona-Reference-Cited by-同舟云学术

Culture of Clinical Specimens Reveals Extensive Diversity of Legionella pneumophila Strains in Arizona

Published:2019-02-27 Issue:1 Volume:4 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Raphael Brian H.¹^ORCID,Huynh Trung²,Brown Ellen¹,Smith Jessica C.¹,Ruberto Irene²,Getsinger Linda²,White Stacy²,Winchell Jonas M.¹

Affiliation:

1. Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

2. Arizona Department of Health Services, Phoenix, Arizona, USA

Abstract

Culture of clinical specimens from patients with Legionnaires’ disease is rarely performed, restricting our understanding of the diversity and ecology of Legionella . Culture of Legionella from patient specimens in Arizona revealed a greater proportion of non-serogroup 1 Legionella pneumophila isolates than in other U.S. isolates examined. Disease caused by such isolates may go undetected using other diagnostic methods. Moreover, genome sequence analysis revealed that these isolates were genetically diverse, and understanding these populations may help in future environmental source attribution studies.

Funder

HHS | Centers for Disease Control and Prevention

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00649-18

Reference21 articles.

1. Summary of Notifiable Infectious Diseases and Conditions — United States, 2013

2. Final 2014 Reports of Nationally Notifiable Infectious Diseases

3. Centers for Disease Control and Prevention. 2018. National Notifiable Disease Surveillance System (NNDSS). CDC, Atlanta, GA. https://www.cdc.gov/nndss/infectious-tables.html.

4. Current and Emerging Legionella Diagnostics for Laboratory and Outbreak Investigations

5. Evaluation and Comparison of Multiple Test Methods, Including Real-time PCR, for Legionella Detection in Clinical Specimens

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Evaluation of Genetic Diversity and Virulence Potential of Legionella pneumophila Isolated from Water Supply Systems of Residential Buildings in Latvia;Pathogens;2023-06-28

2. Clinical and Laboratory Diagnosis of Legionella Pneumonia;Diagnostics;2023-01-12

3. Presence of Viable, Clinically Relevant Legionella Bacteria in Environmental Water and Soil Sources of China;Microbiology Spectrum;2022-06-29

4. Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains;Life Science Alliance;2022-03-02

5. Risk Factors, Management, and Outcomes of Legionella Pneumonia in a Large, Nationally Representative Sample;Chest;2021-05