Identification of Genes Required for Long-Term Survival of Legionella pneumophila in Water

Author:

Aurass Philipp12ORCID,Kim Seongok2,Pinedo Victor3,Cava Felipe3ORCID,Isberg Ralph R.2ORCID

Affiliation:

1. Department of Enteropathogenic Bacteria and Legionella, Robert Koch Institute, Wernigerode, Germany

2. Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA

3. Laboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, Umeå Centre for Microbial Research, Umeå University, Umeå, Sweden

Abstract

Water is the primary vector for transmission of L. pneumophila to humans, and the pathogen is adapted to persist in this environment for extended periods of time. Preventing survival of L. pneumophila in water is therefore critical for prevention of Legionnaires’ disease.

Funder

Deutsche Forschungsgemeinschaft

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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