Author:
Ackland N R,Tannock G A,Young I F
Abstract
A device for the decontamination of large numbers of infected eggs which remain as by-products of vaccine production is described. Homogenates of infected eggs were heated to 60 degrees C and maintained at that temperature for 3 h in a specially constructed recirculation tank. The infectivity of all detectable influenza viruses and more than 99% of the bacteria associated with the homogenates was destroyed by this procedure. Eggshell material was separated from the proteins present in the homogenate at the end of the heating cycle by means of a cyclone separator. The proportions of all the amino acids, except cystine, in the proteins remaining in the suspension after the heating cycle were similar to that normally present in whole embryos.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
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