Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release-Reference-Cited by-同舟云学术

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Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release

Published:2022-12-21 Issue:24 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Domanska Aušra¹^ORCID,Plavec Zlatka¹,Ruokolainen Visa²,Löflund Benita¹,Marjomäki Varpu²,Butcher Sarah J.¹^ORCID

Affiliation:

1. Faculty of Biological and Environmental Sciences, Molecular and Integrative Bioscience Research Programme, and Helsinki Institute of Life Sciences-Institute of Biotechnology, University of Helsinki, Helsinki, Finland

2. Department of Biological and Environmental Sciences, Nanoscience Center, University of Jyväskylä, Jyväskylä, Finland

Abstract

Coxsackievirus A9 (CVA9) is a common cause of meningitis and neonatal sepsis. The triggers and mode of action of RNA release into the cell unusually do not require receptor interaction.

Funder

Academy of Finland

Sigrid Juselius Foundation

Jane and Aatos Erkko Foundation

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01367-22

Reference69 articles.

1. Viruses Causing Aseptic Meningitis: A Tertiary Medical Center Experience With a Multiplex PCR Assay

2. Clinical features and phylogenetic analysis of Coxsackievirus A9 in Northern Taiwan in 2011

3. Assessment of blood enterovirus PCR testing in paediatric populations with fever without source, sepsis-like disease, or suspected meningitis: a prospective, multicentre, observational cohort study

4. Echovirus 30 and coxsackievirus A9 infection among young neonates with sepsis in Iran;Shabani A;Iran J Microbiol,2018

5. Picornavirus Morphogenesis

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