Cytomegalovirus homologs of cellular G protein-coupled receptor genes are transcribed

Author:

Welch A R1,McGregor L M1,Gibson W1

Affiliation:

1. Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland 21205.

Abstract

The genome of human cytomegalovirus (HCMV) contains three genes with homology to cellular G protein-coupled receptors (GCRs). Evidence is presented here that all three HCMV GCR genes are transcribed during infection, that they are transcribed as two sets of 3'-coterminal mRNAs, and that their transcription is restricted to the late phase of infection.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference11 articles.

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3. Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169;Chee M. S.;Curr. Top. Microbiol. Immunol.,1990

4. Human cytomegalovirus encodes three G protein-coupled receptor homologues;Chee M. S.;Nature (London),1990

5. Colberg-Poley A. M. and L. D. Santomenna. 1988. Selective 3918 NOTES

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