Increasing Incidence of Streptococcus pneumoniae Serotype 19A and Emergence of Two Vaccine Escape Recombinant ST695 Strains in Liguria, Italy, 7 Years after Implementation of the 7-Valent Conjugated Vaccine

Author:

Ansaldi Filippo123,Canepa Paola123,de Florentiis Daniela123,Bandettini Roberto123,Durando Paolo123,Icardi Giancarlo123

Affiliation:

1. Department of Health Sciences, University of Genoa, Genoa, Italy

2. San Martino University Hospital, Genoa, Italy

3. I.R.C.C.S. Giannina Gaslini, Genoa, Italy

Abstract

ABSTRACT Two serotype 19A (ST695) Streptococcus pneumoniae vaccine escape recombinant strains attributable to capsular switching events were detected by a laboratory surveillance system that is an integral part of a vaccination program begun in Liguria, Italy, in May 2003, an Italian administrative region with long-lasting high coverage, an unusual occurrence in Europe. To our knowledge, this is the first detection of an occurrence of capsular switching outside the United States.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

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