Author:
Pugashetti B K,Vadas L,Prihar H S,Feingold D S
Abstract
GDPmannose dehydrogenase (EC 1.1.1.132) in a mucoid strain of Pseudomonas aeruginosa isolated from a patient with cystic fibrosis was identified by demonstrating the NAD-linked formation of GDPmannuronate from GDPmannose mediated by a cell extract of the organism. Nonmucoid mutant strains did not contain GDPmannose dehydrogenase, which suggests that the enzyme is involved in the biosynthesis of alginate-like polysaccharide by P. aeruginosa.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
31 articles.
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