Genes and Proteins Involved in qnrS1 Induction-Reference-Cited by-同舟云学术

Genes and Proteins Involved in qnrS1 Induction

Published:2018-09 Issue:9 Volume:62 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Monárrez Rubén¹,Wang Yin¹,Fu Yingmei¹²,Liao Chun-Hsing¹³,Okumura Ryo¹⁴,Braun Molly R.¹,Jacoby George A.⁵,Hooper David C.¹

Affiliation:

1. Division of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA

2. Department of Microbiology, Heilongjiang Provincial Key Laboratory for Infection and Immunity, Harbin Medical University, Harbin, China

3. Far Eastern Memorial Hospital, Taipei, Taiwan

4. Biological Research Laboratories, Daiichi Sankyo Co. Ltd., Tokyo, Japan

5. Lahey Hospital and Medical Center, Burlington, Massachusetts, USA

Abstract

Expression of the quinolone resistance gene qnrS1 is increased by quinolones, but unlike induction of some other qnr genes, the bacterial SOS system is not involved and no lexA box is found upstream. Nonetheless, at least 205 bp of upstream sequence is required for induction to take place.

Funder

HHS | National Institutes of Health

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00806-18

Reference45 articles.

1. The worldwide emergence of plasmid-mediated quinolone resistance

2. Plasmid-Mediated Quinolone Resistance