Development of a Rapid and Convenient Method for Determination of Rubella Virus-Specific Immunoglobulin G Avidity-Reference-Cited by-同舟云学术

Development of a Rapid and Convenient Method for Determination of Rubella Virus-Specific Immunoglobulin G Avidity

Published:2007-11 Issue:11 Volume:14 Page:1416-1419
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Vauloup-Fellous Christelle¹²,Ursulet-Diser Jessica¹²,Grangeot-Keros Liliane¹²

Affiliation:

1. Faculty of Medicine Paris-Sud, University Paris-Sud 11, Le Kremlin-Bicêtre F-94276, France

2. Department of Microbiology and Immunology, AP-HP, Antoine Béclère Hospital, Clamart F-92141, France

Abstract

ABSTRACT We describe here a rapid and semiautomated method for the determination of rubella virus immunoglobulin G (IgG) avidity with the VIDAS instrument. A total of 153 serum samples from persons with naturally acquired rubella virus infections ( n = 98), from vaccinated persons ( n = 44), and from patients with autoantibodies ( n = 11) were included in this study. The rubella virus-specific IgG avidity assay we developed for the VIDAS instrument was evaluated by comparison with an in-house method. Results obtained with the VIDAS instrument allow considering this method valuable to help confirm or exclude acute primary infection or recent vaccination.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CVI.00312-07

Reference15 articles.

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