Disparity Between Inhibitory and Killing Effects of BL-P1654

Author:

Kurtz Stephen1,Holmes King1,Turck Marvin1

Affiliation:

1. Department of Medicine, University of Washington, and Harborview Medical Center, Seattle, Washington 98104

Abstract

The activity of BL-P1654, a semisynthetic penicillin, was studied in vitro against Enterobacteriaceae and compared with carbenicillin against Pseudomonas . There was a marked diminution in bactericidal activity of BL-P1654 when tested in broth medium.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference9 articles.

1. In vitro studies of semisynthetic a-(substituted-ureido) penicillins;Bodey G. P.;Appl. Microbiol.,1971

2. Price K. E. F. Leitner M. Misiek D. R. Chisholm and T. A. Pursiano. 1971. BL-P 1654 a new broad-spectrum penicillin with marked antipseudomonal activity p. 17-29. Antimicrob. Agents Chemother. 1970.

3. Silverblatt F. and M. Turck. 1969. Laboratory and clinical evaluation of carbenicillin (carboxybenzyl penicillin) p. 279-285. Antimicrob. Agents Chemother. 1968.

4. An inocula replicating apparatus for routine testing of bacterial susceptibility of antibiotics;Steers E.;Antibiot. Chemother.,1959

5. Van Scoy R. E. E. Warren and J. A. Washington II. 1971.

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