Affiliation:
1. Department of Medicine, University of Washington, Seattle, Washington
Abstract
ABSTRACT
Putative adhesins were predicted by computer analysis of the
Treponema pallidum
genome. Two treponemal proteins, Tp0155 and Tp0483, demonstrated specific attachment to fibronectin, blocked bacterial adherence to fibronectin-coated slides, and supported attachment of fibronectin-producing mammalian cells. These results suggest Tp0155 and Tp0483 are fibronectin-binding proteins mediating
T. pallidum
-host interactions.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
69 articles.
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