Comparative susceptibilities of Campylobacter pylori to norfloxacin and other agents

Author:

Shungu D L,Nalin D R,Gilman R H,Gadebusch H H,Cerami A T,Gill C,Weissberger B

Abstract

Twenty-one strains of Campylobacter pylori (Campylobacter pyloridis) were tested for susceptibility to norfloxacin and other agents by the serial agar dilution method. Ampicillin (MIC for 90% of isolates [MIC90], 0.016 micrograms/ml) and famotidine (MIC90, greater than 1,024 micrograms/ml) were, respectively, the most and the least active of the agents tested. Norfloxacin (MIC90, 1 microgram/ml) and imipenem (MIC90, 0.125 micrograms/ml) were substantially active against this organism.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference10 articles.

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2. Famotidine: pharmacodynamic and pharmokinetic properties and a preliminary review of its therapeutic use in peptic ulcer disease and Zollinger-Ellison syndrome;Campoli-Richards D. M.;Drugs,1986

3. The minimum inhibitory and bactericidal concentrations of antibiotics and anti-ulcer agents against Campylobacter pyloridis;Goodwin C. S.;J. Antimicrob. Chemother.,1986

4. Norfloxacin, a review of its antibacterial activity, pharmacokinetic properties and therapeutic use;Holmes B.;Drug Evaluation,1985

5. Antibiotic sensitivity of Campylobacter pyloridis;Kasper G.;Eur. J. Clin. Microbiol.,1985

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