Affiliation:
1. Environmental Protection Group, U.S. Army Natick Research and Development Laboratories, Natick, Massachusetts 01760
Abstract
When calcium hydroxide is used to desensitize glycerol trinitrate (nitroglycerine)-containing waste streams, the epoxides glycidol and glycidyl nitrate are formed. The epoxide rings of both compounds are unstable to heat in aqueous solutions, and they open to form glycerol 1-mononitrate and presumably glycerol. These transformations were accelerated by microbial activity. Glycerol 1-mononitrate was slowly denitrated to form glycerol. Glycidol and glycidyl nitrate caused base-pair substitutions in the Ames test for mutagenicity, whereas glycerol 1-mononitrate tests were negative.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Reference13 articles.
1. Ames B. N. 1979. Supplement to the methods paper p. 1-10. University of California Berkeley.
2. Methods of detecting carcinogens and mutagens with the Salmonella mammalian-microsome mutagenicity test;Ames B. N.;Mut. Res.,1975
3. Fluorescence study of DNA alkylation epoxides;Hemminiki K.;Chem. Biol. Interact.,1979
4. Direction of addition of the nitrate ion to an unsymmetrical oxide;Ingham J. D.;Am. Chem. Soc. J.,1954
5. Study of toxicity, hazard, and harmful effects of glycidol on animals;Ivanov N. G.;Gig. Tr. Prof. Zabol.,1980
Cited by
16 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Glycidol;Encyclopedia of Toxicology;2024
2. Glycidol;Encyclopedia of Toxicology;2014
3. Bioremediation of Nitroglycerin: State of the Science;Environmental Science and Engineering;2013-08-02
4. Glycidol [MAK Value Documentation, 2003];The MAK-Collection for Occupational Health and Safety;2012-01-31
5. Glycidol [MAK Value Documentation in German language, 2000];The MAK-Collection for Occupational Health and Safety;2012-01-31