Effect of azlocillin on uric acid levels in serum

Author:

Ernst J A,Sy E R

Abstract

Uric acid levels in serum were observed to fall precipitously in a group of 20 hospitalized asthmatic patients receiving azlocillin, bronchodilators, and steroids. None of the 20 hospitalized controls receiving the antiasthma therapy without azlocillin showed any decline in their uric acid levels. The levels for the azlocillin-treated group fell from a mean of 6.4 mg/dl to mean of 2.3 mg/dl, whereas those for the control group initially were 7.0 mg/dl and fell only to a mean of 6.5 mg/dl.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference5 articles.

1. Chonko A. and J. Grantham. 1981. Disorders of urate metabolism and excretion p. 1023-1055. In B. Brenner and F. Rector (ed.) The kidney. The W. B. Saunders Co. Philadelphia Pa.

2. Azlocillin and serum uric acid;Faris H. M., Jr.;Ann. Intern. Med.,1983

3. Miles Laboratories Inc. Azlocillin Investigators Manual. 1980. Miles Laboratories Inc. West Haven Conn.

4. Absorption and excretion of penicillin following continuous intravenous and subcutaneous administration;Rantz L. S.;J. Clin. Invest.,1944

5. Stanbury J. B J. B. Wyngaarden and D. S. Fredrikson (ed.). 1972. The metabolic basis of inherited disease 3rd ed. p. 330. McGraw-Hill Book Co. New York.

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