Identification of Potential Recombination Breakpoints in Human Parechoviruses-Reference-Cited by-同舟云学术

Identification of Potential Recombination Breakpoints in Human Parechoviruses

Published:2009-04 Issue:7 Volume:83 Page:3379-3383
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Zoll Jan¹,Galama Jochem M. D.¹,van Kuppeveld Frank J. M.¹

Affiliation:

1. Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands

Abstract

ABSTRACT Based on a comparison of the phylogeny of two distant regions, evidence has been found for recombination within parechoviruses. However, recombination breakpoints could not be detected in this way. We searched for potential recombination breakpoints in parechovirus by analysis of complete parechovirus sequences, including a newly isolated strain. Bootscan analysis demonstrated that parechoviruses are mosaic viruses build of regions related to corresponding genomic regions of other parechoviruses. With a genetic algorithm for recombination detection, sites for recombination were found. Analysis of partial sequences, as defined by recombination breakpoints, showed phylogenetic segregation between regions.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.02529-08

Reference32 articles.

1. Abed, Y., and G. Boivin. 2005. Molecular characterization of a Canadian human parechovirus (HPeV)-3 isolate and its relationship to other HPeVs. J. Med. Virol.77:566-570.

2. Agol, V. I. 1997. Recombination and other genomic rearrangements in picornaviruses. Semin. Virol.8:1-9.

3. Analysis of a New Human Parechovirus Allows the Definition of Parechovirus Types and the Identification of RNA Structural Domains

4. Bedard, K. M., and B. L. Semler. 2004. Regulation of picornavirus expression. Microbes Infect.6:702-713.

5. Benschop, K. S. M., J. Schinkel, M. E. Luken, P. J. M. van den Broek, M. F. C. Beersma, N. Menelik, H. W. M. van Eijk, H. L. Zaaijer, C. M. J. E. VandenBroucke-Grauls, M. G. H. M. Beld, and K. C. Wolthers. 2006. Fourth human parechovirus serotype. Emerg. Infect. Dis.12:1572-1575.

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