Affiliation:
1. Laboratory of Metalloprotein Biology, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland
Abstract
ABSTRACT
A new study by Nies et al. (J Bacteriol 206:e00080-24, 2024,
https://doi.org/10.1128/jb.00080-24
) provides a rich, quantitative data set of zinc accumulation by cells of
Cupriavidus metallidurans
, including of mutant bacterial strains lacking import or efflux genes, and comparison of zinc accumulation by cells previously starved of metal with those of zinc-replete cells. The data surprisingly demonstrate the concomitant activity of both active metal import and metal efflux systems. They present a flow equilibrium model to describe zinc homeostasis in bacteria.
Funder
Narodowe Centrum Nauki
HHS | National Institutes of Health
Publisher
American Society for Microbiology