Managing All the Genotypic Knowledge: Approach to a Septic Patient Colonized by Different Enterobacteriales with Unique Carbapenemases-Reference-Cited by-同舟云学术

Managing All the Genotypic Knowledge: Approach to a Septic Patient Colonized by Different Enterobacteriales with Unique Carbapenemases

Published:2019-08 Issue:8 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Park Stacy C.¹^ORCID,Wailan Alexander M.¹,Barry Katie E.¹,Vegesana Kasi²,Carroll Joanne³,Mathers Amy J.¹³^ORCID,Miller William R.⁴⁵,Munita Jose M.⁴⁵⁶⁷

Affiliation:

1. Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA

2. Health Information & Technology, University of Virginia Health System, Charlottesville, Virginia, USA

3. Clinical Microbiology Laboratory, Department of Pathology, University of Virginia Health System, Charlottesville, Virginia, USA

4. Center for Antimicrobial Resistance and Microbial Genomics, University of Texas Health Science Center, Houston, Texas, USA

5. Division of Infectious Diseases, McGovern Medical School, University of Texas Health Science Center, Houston, Texas, USA

6. Genomics and Resistant Microbes Group, Facultad de Medicina Clinica Alemana, Universidad del Desarrollo, Santiago, Chile

7. Millennium Initiative for Collaborative Research on Bacterial Resistance (MICROB-R), Millennium Science Initiative, Santiago, Chile

Abstract

The recent development of new antimicrobials active against carbapenemase-producing Enterobacteriales (CPE) has brought new hope for the treatment of infections due to these organisms. However, the evolving epidemiology of bacteria with carbapenemases may complicate management, as providers are faced with treating patients colonized by bacteria producing multiple carbapenemases.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00029-19

Reference22 articles.

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3. Phenotypic and Genotypic Characterization ofEnterobacteriaceaeProducing Oxacillinase-48–Like Carbapenemases, United States