The Complex Link between the Female Genital Microbiota, Genital Infections, and Inflammation

Author:

Dabee Smritee1ORCID,Passmore Jo-Ann S.234,Heffron Renee5,Jaspan Heather B.125ORCID

Affiliation:

1. Seattle Children’s Research Institute, Seattle, Washington, USA

2. Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa

3. CAPRISA Centre of Excellence in HIV Prevention, University of Cape Town, Cape Town, South Africa

4. National Health Laboratory Service, Cape Town, South Africa

5. University of Washington, Seattle, Washington, USA

Abstract

The female genital tract microbiota is part of a complex ecosystem influenced by several physiological, genetic, and behavioral factors. It is uniquely linked to a woman’s mucosal immunity and plays a critical role in the regulation of genital inflammation.

Funder

EDCTP

NIH

South African Department of Science and Technology

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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