EUCAST-Obtained Olorofim MICs against Aspergillus and Scedosporium Species and Lomentospora prolificans Showed High Agreements between Visual Inspection and Spectrophotometric Readings-Reference-Cited by-同舟云学术

EUCAST-Obtained Olorofim MICs against Aspergillus and Scedosporium Species and Lomentospora prolificans Showed High Agreements between Visual Inspection and Spectrophotometric Readings

Published:2022-09-20 Issue:9 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Escribano Pilar¹²^ORCID,Gómez Ana¹²^ORCID,Reigadas Elena¹²³⁴^ORCID,Muñoz Patricia¹²³⁴^ORCID,Guinea Jesús¹²³^ORCID

Affiliation:

1. Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain

2. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain

3. CIBER Enfermedades Respiratorias-CIBERES (CB06/06/0058), Madrid, Spain

4. Department of Medicine, Faculty of Medicine, Universidad Complutense de Madrid, Madrid, Spain

Abstract

Previous studies show high agreement between MIC spectrophotometric readings and visual inspection of azoles and amphotericin B against Aspergillus fumigatus isolates. Here, we tested and compared the in vitro activity of a novel antifungal, olorofim, against Aspergillus spp., Scedosporium spp., and Lomentospora prolificans by visual inspection and spectrophotometric readings.

Funder

Fondo de Investigacion Sanitaria

F2G Inc., Manchester, UK

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.00849-22

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