Decreasing Prevalence of β-Lactamase Production among Respiratory Tract Isolates of Haemophilus influenzae in the United States

Author:

Heilmann Kris P.1,Rice Cassie L.1,Miller Ashley L.1,Miller Norma J.1,Beekmann Susan E.1,Pfaller Michael A.1,Richter Sandra S.1,Doern Gary V.1

Affiliation:

1. Division of Medical Microbiology, Department of Pathology, Roy J. and Lucille A. Carver University of Iowa College of Medicine, Iowa City, Iowa

Abstract

ABSTRACT A total of 986 isolates of Haemophilus influenzae from patients with respiratory tract infections in 45 United States medical centers were characterized during the winter of 2002-2003. β-Lactamase production was noted with 26.2% of isolates; 14.6% were resistant to trimethoprim-sulfamethoxazole. Resistance to other relevant antimicrobial agents was extremely uncommon. In comparison to the results of four previous national surveys conducted since 1994, the prevalence of β-lactamase production with this pathogen appears to be decreasing.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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