Novel Lytic Phages Protect Cells and Mice against Pseudomonas aeruginosa Infection-Reference-Cited by-同舟云学术

Novel Lytic Phages Protect Cells and Mice against Pseudomonas aeruginosa Infection

Published:2021-03-25 Issue:8 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Chen Feng¹,Cheng Xingjun²³⁴,Li Jianbo¹,Yuan Xiefang¹,Huang Xiuhua²³⁴,Lian Mao²³⁴,Li Wenfang²³⁴,Huang Tianfang⁵,Xie Yaliu⁶,Liu Jie²³⁴⁷,Gao Pan²³⁴,Wei Xiawei²³⁴,Wang Zhenling²³⁴^ORCID,Wu Min¹⁸^ORCID

Affiliation:

1. Respiratory Department, Allergy and Immunity Institute, Affiliated Hospital, Southwest Medical University, Luzhou, China

2. State Key Laboratory of Biotherapy, Sichuan University, Chengdu, China

3. Cancer Center, West China Hospital, Sichuan University, Chengdu, China

4. Collaborative Innovation Center of Biotherapy, Chengdu, China

5. Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China

6. Department of Otolaryngology, The Seventh People’s Hospital of Chengdu, Chengdu, China

7. Lab of Infectious Diseases and Vaccines, West China Hospital, Sichuan University, Chengdu, China

8. Department of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota, USA

Abstract

Novel lytic phages isolated from various environmental settings were systematically characterized for their critical genetic traits, morphology structures, host ranges against laboratory strains and clinical multidrug-resistant (MDR) Pseudomonas aeruginosa isolates, and antibacterial capacity both in vitro and in mouse models. First, we characterized the genetic traits and compared them with those of other existing phages.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01832-20

Reference58 articles.

1. Bacteriophages ϕMR299-2 and ϕNH-4 Can Eliminate Pseudomonas aeruginosa in the Murine Lung and on Cystic Fibrosis Lung Airway Cells

2. Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China

3. Predictive factors for multidrug-resistant gram-negative bacteria among hospitalised patients with complicated urinary tract infections

4. Antibacterial Efficacy of Phages against Pseudomonas aeruginosa Infections in Mice and Drosophila melanogaster

5. A megaplasmid family driving dissemination of multidrug resistance in Pseudomonas

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Pharmacokinetics and pharmacodynamics of bacteriophage therapy: a review with a focus on multidrug-resistant Gram-negative bacterial infections;Clinical Microbiology Reviews;2024-09-12

2. Isolation and Characterization of Three Lytic Bacteriophages to Overcome Multidrug-, Extensive Drug-, and Pandrug-Resistant Pseudomonas aeruginosa;PHAGE;2024-07-30

3. In vivo efficacy of phage cocktails against carbapenem resistance Acinetobacter baumannii in the rat pneumonia model;Journal of Virology;2024-07-23

4. Phage therapy: an alternative treatment modality for MDR bacterial infections;Infectious Diseases;2024-07-17

5. Pseudomonas aeruginosa Bacteriophages and Their Clinical Applications;Viruses;2024-06-29