Affiliation:
1. INSERM E0004-Laboratoire de Recherche Moléculaire sur les Antibiotiques, UFR Broussais-Hôtel Dieu and Pitié Salpétrière, UniversitéParis VI, Paris,1 and
2. Laboratoire de Bactériologie, Centre Hospitalier Intercommunal, Villeneuve-Saint Georges,2 France
Abstract
ABSTRACT
Two novel insertion sequences (IS), IS
1187
and IS
1188
, are described upstream from the carbapenem resistance gene
cfiA
in strains of
Bacteroides fragilis
. Mapping, with the RACE procedure, of transcription start sites of
cfiA
in these and two other previously reported IS showed that transcription of this rarely encountered gene is initiated close to a variety of
B. fragilis
consensus promoter sequences, as recently defined (D. P. Bayley, E. R. Rocha, and C. J. Smith, FEMS Microbiol. Lett. 193:149–154, 2000). In the cases of IS
1186
and IS
1188
, these sequences overlap with putative Eς
70
promoter sequences, while in IS
942
and IS
1187
such sequences can be observed either upstream or downstream of the
B. fragilis
promoters.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
49 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献