Comparison of a Ligase Chain Reaction-Based Assay and Cell Culture for Detection of Pharyngeal Carriage ofChlamydia trachomatis

Author:

Winter Andrew J.1,Gilleran Gerry1,Eastick Kirstine2,Ross Jonathan D. C.1

Affiliation:

1. Department of Genitourinary Medicine, Whittall St. Clinic, Birmingham, 1 and

2. Public Health Laboratory Service Genitourinary Infections Reference Laboratory, Bristol, 2 United Kingdom

Abstract

In 264 genitourinary medicine clinic attenders reporting recent fellatio, the prevalence of pharyngeal Chlamydia trachomatis determined by an expanded standard including cell culture and two in-house PCR tests was 1.5% in 194 women and zero in 70 men. The ligase chain reaction (Abbott LCx) had a specificity of 99.2% and a positive predictive value of 60%.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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