Characterization of Neisseria gonorrhoeae Strains with Decreased Susceptibility to Fluoroquinolones Isolated in Greece from 1996 to 1999

Author:

Mavroidi Angeliki1,Tzouvelekis Leonidas S.2,Tassios Panayotis T.2,Flemetakis Alexandros3,Daniilidou Maria4,Tzelepi Eva1

Affiliation:

1. National Reference Center for Neisseria gonorrhoeae, Department of Bacteriology, Hellenic Pasteur Institute, 1

2. Laboratory of Antimicrobial Agents, Department of Microbiology, Athens University Medical School, 2 and

3. Microbiology Laboratory of the “Andreas Sygros” Hospital for Skin and Venereal Diseases, 3 Athens, and

4. Microbiology Laboratory of the Venereal Hospital of Thessaloniki, Thessaloniki, 4 Greece

Abstract

Of the 331 Neisseria gonorrhoeae strains isolated in Greece from 1996 to 1999, 39 (11.8%) exhibited decreased susceptibility to quinolones due to gyrA andparC mutations. Conventional typing and pulsed-field gel electrophoresis showed that 34 of these isolates were clonally related. Epidemiological data indicated that the epidemic clone was sustained in a group of high-frequency transmitters.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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