Draft Genome Sequence of an Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis from Nepal-Reference-Cited by-同舟云学术

Draft Genome Sequence of an Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis from Nepal

Published:2020-01-23 Issue:4 Volume:9 Page:
ISSN:2576-098X
Container-title:Microbiology Resource Announcements
language:en
Short-container-title:Microbiol Resour Announc

Author:

Gautam Sanjay S.¹,Leong Kelvin W. C.²,Pradhan Manoj³,Singh Y. Ibotomba³,Rajbhandari Sagar K.⁴,Ghimire Gokarna R.⁴,Adhikari Krishna⁴,Shrestha Uma⁴,Chaudhary Raina³,Ghimire Gyanendra³,Khadka Sundar⁵,O’Toole Ronan F.²⁶

Affiliation:

1. School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania, Australia

2. School of Molecular Sciences, College of Science, Health and Engineering, La Trobe University, Victoria, Australia

3. Department of Microbiology, College of Medicine, Nepalese Army Institute of Health Sciences, Kathmandu, Nepal

4. National Tuberculosis Control Center, Bhaktapur, Nepal

5. HIV Reference Unit, National Public Health Laboratory, Kathmandu, Nepal

6. Trinity College Dublin, Department of Clinical Microbiology, Saint James’s Hospital, Dublin, Ireland

Abstract

Extensively drug-resistant (XDR) Mycobacterium tuberculosis has become a challenge to the treatment of tuberculosis (TB) in several countries, including Nepal. Here, we report for the first time the draft genome sequence of an isolate of XDR-TB collected in Nepal and describe single-nucleotide variations associated with its extensively drug-resistant phenotype.

Funder

La Trobe University

Publisher

American Society for Microbiology

Subject

Genetics,Immunology and Microbiology (miscellaneous),Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/MRA.01404-19

Reference18 articles.

1. World Health Organization. 2019. Global tuberculosis report. World Health Organization, Geneva, Switzerland.

2. Ministry of Health, Government of Nepal. 2016. National strategic plan for tuberculosis prevention, care and control 2016–2021. Ministry of Health, Government of Nepal, Kathmandu, Nepal.

3. World Health Organization. 2018. Global tuberculosis report. World Health Organization, Geneva, Switzerland.

4. Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in New Zealand

5. Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland