Detection of Measles Virus mRNA from Autopsied Human Tissues-Reference-Cited by-同舟云学术

Detection of Measles Virus mRNA from Autopsied Human Tissues

Published:1998-01 Issue:1 Volume:36 Page:299-301
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Katayama Yuko¹,Kohso Kiyoyasu¹,Nishimura Akiyoshi²,Tatsuno Yoshitsugu³,Homma Morio⁴,Hotta Hak¹

Affiliation:

1. Department of Microbiology,1 and

2. Department of Legal Medicine, Shiga University of Medical Science, Ohtsu, Shiga 520-21,2 and

3. Department of Legal Medicine,3 Kobe University School of Medicine, Chuo-ku, Kobe, Hyogo 650,

4. Faculty of Home Economics, Kobe Women’s University, Suma-ku, Kobe, Hyogo 654,4 Japan

Abstract

ABSTRACT By reverse transcription-PCR, measles virus (MV) mRNA was detected in the brain, kidney, spleen, liver, and lung tissues obtained from 23 (45.1%) of 51 autopsy subjects, with the detection rates of each tissue ranging from 8 to 20%. Sequence analysis revealed frequent mutations in the corresponding viral protein. These results suggest that MV mutants commonly persist in apparently healthy individuals.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.36.1.299-301.1998

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