Absolute Copy Number and Relative Change in Determinations of Human Immunodeficiency Virus Type 1 RNA in Plasma: Effect of an External Standard on Kit Comparisons-Reference-Cited by-同舟云学术

Absolute Copy Number and Relative Change in Determinations of Human Immunodeficiency Virus Type 1 RNA in Plasma: Effect of an External Standard on Kit Comparisons

Published:1998-01 Issue:1 Volume:36 Page:311-314
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Brambilla Donald¹,Leung Sheila¹,Lew Judy²,Todd John³,Herman Steven⁴,Cronin Mike⁵,Shapiro David E.⁶,Bremer James⁷,Hanson Celine⁸,Hillyer George V.⁹,McSherry George D.¹⁰,Sperling Rhoda S.¹¹,Coombs Robert W.¹²,Reichelderfer Patricia S.²

Affiliation:

1. New England Research Institutes, Watertown, Massachusetts 021721;

2. National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 208922;

3. Chiron Corporation, Emeryville, California 946083;

4. Roche Molecular Systems, Branchburg, New Jersey 088764;

5. Organon Teknika Corporation, Durham, North Carolina 277125;

6. Harvard School of Public Health, Boston, Massachusetts 021156;

7. Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois 606127;

8. Baylor College of Medicine, Houston, Texas 770308;

9. University of Puerto Rico School of Medicine, San Juan, Puerto Rico 00936-50679;

10. UMD-New Jersey Medical School, Newark, New Jersey 0710310;

11. Mount Sinai Medical Center, New York, New York 1002911; and

12. University of Washington, Seattle, Washington 9819512

Abstract

ABSTRACT Use of a common set of human immunodeficiency virus type 1 (HIV-1) RNA standards eliminated differences among absolute HIV-1 RNA copy number estimates made with three commercially available assays. The relative changes in the viral RNA levels determined by the commercial assays were similar and were unaffected by the use of a common set of standards.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.36.1.311-314.1998

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