Identification of Novel Bacteriophages with Therapeutic Potential That Target Enterococcus faecalis-Reference-Cited by-同舟云学术

Identification of Novel Bacteriophages with Therapeutic Potential That Target Enterococcus faecalis

Published:2019-11 Issue:11 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Al-Zubidi M.¹,Widziolek M.¹²,Court E. K.¹,Gains A. F.¹,Smith R. E.³,Ansbro K.¹,Alrafaie A.¹,Evans C.⁴,Murdoch C.¹,Mesnage S.³,Douglas C. W. I.¹,Rawlinson A.¹,Stafford G. P.¹

Affiliation:

1. Integrated BioSciences, School of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom

2. Department of Microbiology, Faculty of Biochemistry, Biophysics, and Biotechnology, Jagiellonian University, Cracow, Poland

3. Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, United Kingdom

4. Department of Chemical and Biological Engineering, The University of Sheffield, Sheffield, United Kingdom

Abstract

The Gram-positive opportunistic pathogen Enterococcus faecalis is frequently responsible for nosocomial infections in humans and represents one of the most common bacteria isolated from recalcitrant endodontic (root canal) infections. E. faecalis is intrinsically resistant to several antibiotics routinely used in clinical settings (such as cephalosporins and aminoglycosides) and can acquire resistance to vancomycin (vancomycin-resistant enterococci).

Funder

UK Research and Innovation | Biotechnology and Biological Sciences Research Council

UK Research and Innovation | Engineering and Physical Sciences Research Council

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00512-19

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