Capnocytophaga ochracea : Characterization of a Plasmid-Encoded Extended-Spectrum TEM-17 β-Lactamase in the Phylum Flavobacter-Bacteroides-Reference-Cited by-同舟云学术

Capnocytophaga ochracea : Characterization of a Plasmid-Encoded Extended-Spectrum TEM-17 β-Lactamase in the Phylum Flavobacter-Bacteroides

Published:2000-03 Issue:3 Volume:44 Page:760-762
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Rosenau Agnes¹,Cattier Blandine¹,Gousset Nathalie¹,Harriau Patrick¹,Philippon Alain²,Quentin Roland¹

Affiliation:

1. Département de Microbiologie Médicale et Moléculaire, Centre Hospitalier Universitaire Bretonneau, 37044 Tours cedex,1 and

2. Service de Bactériologie, Hôpital Cochin (Université Paris V), 75679 Paris cedex 14,2 France

Abstract

ABSTRACT A plasmid-encoded extended-spectrum TEM β-lactamase with a pI of 5.5 was detected in a Capnocytophaga ochracea clinical isolate. The bla gene was associated with a strong TEM-2 promoter and was derived from bla TEM-1a with a single-amino-acid substitution: Glu 104 →Lys, previously assigned to TEM-17, which is thus the first TEM β-lactamase to be reported in the phylum Flavobacter-Bacteroides .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.44.3.760-762.2000

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