Comparative Evaluation of Piperacillin in Vitro-Reference-Cited by-同舟云学术

Comparative Evaluation of Piperacillin in Vitro

Published:1978-12 Issue:6 Volume:14 Page:919-921
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Dickinson Gordon M.¹,Cleary Timothy J.¹,Hoffman Thomas A.²

Affiliation:

1. Department of Pathology, University of Miami School of Medicine, Miami, Florida 33152

2. Department of Medicine, Division of Infectious Diseases, University of Miami School of Medicine, Miami, Florida 33152

Abstract

The minimal inhibitory concentrations of piperacillin and seven other betalactam antibiotics were determined against 407 bacterial isolates. Piperacillin was found to be more active than ampicillin against susceptible gram-negative bacilli and more active than either carbenicillin or ticarcillin against Pseudomonas aeruginosa and streptococci. Although piperacillin was active against Klebsiella pneumoniae , this activity was less than that of the cephalosporins. Piperacillin was not active against penicillin-resistant Staphylococcus aureus and Enterobacteriaceae that were resistant to the other test antibiotics.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.14.6.919

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