Molecular Mechanisms of Conidial Germination in Aspergillus spp

Author:

Baltussen Tim J. H.12ORCID,Zoll Jan12,Verweij Paul E.12,Melchers Willem J. G.12

Affiliation:

1. Department of Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands

2. Center of Expertise in Mycology Radboudumc/CWZ, Nijmegen, the Netherlands

Abstract

Aspergilli produce conidia for reproduction or to survive hostile conditions, and they are highly effective in the distribution of conidia through the environment. In immunocompromised individuals, inhaled conidia can germinate inside the respiratory tract, which may result in invasive pulmonary aspergillosis. The management of invasive aspergillosis has become more complex, with new risk groups being identified and the emergence of antifungal resistance.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology,Infectious Diseases

Reference199 articles.

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