Identification of a Plasmid Encoding SHV-12, TEM-1, and a Variant of IMP-2 Metallo-β-Lactamase, IMP-8, from a Clinical Isolate of Klebsiella pneumoniae-Reference-Cited by-同舟云学术

Identification of a Plasmid Encoding SHV-12, TEM-1, and a Variant of IMP-2 Metallo-β-Lactamase, IMP-8, from a Clinical Isolate of Klebsiella pneumoniae

Published:2001-08 Issue:8 Volume:45 Page:2368-2371
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Yan Jing-Jou¹,Ko Wen-Chien²,Wu Jiunn-Jong³

Affiliation:

1. Departments of Pathology1 and

2. Medicine,2 National Cheng Kung University Medical Center, and

3. Department of Medical Technology,3 National Cheng Kung University Medical College, Tainan, Taiwan

Abstract

ABSTRACT A multidrug-resistant plasmid encoding TEM-1, SHV-12, and a variant of IMP-2 metallo-β-lactamase, designated IMP-8, was identified from a clinical isolate of Klebsiella pneumoniae . There are four nucleotide differences between bla IMP-2 and bla IMP-8 , resulting in two amino acid differences. bla IMP-8 was also found to be carried by an integron-borne gene cassette similar to the bla IMP-2 cassette.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.45.8.2368-2371.2001

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