Persistent Multiple Pulmonary Nodules in a Nonimmunocompromised Woman after Varicella-Related Myelitis Treated with Acyclovir

Author:

Schvoerer Evelyne1,Frechin Valéry1,Warter André2,Gasser Bernard2,Jouin Hervé3,Gut Jean-Pierre1,Stoll-Keller Françoise1

Affiliation:

1. Institut de Virologie de la Faculté de Médecine et Hôpitaux Universitaires de Strasbourg

2. Institut d'Anatomie Pathologique de la Faculté de Médecine et Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg

3. Centre Hospitalier Général Saint Nicolas, 54402 Sarrebourg, France

Abstract

ABSTRACT Persistent multiple pulmonary nodules were observed on the chest X ray of a nonimmunocompromised woman 6 months after she was treated with acyclovir for a varicella-related myelitis without respiratory symptoms. Early antiviral therapy given for varicella infections might decrease the intensity of clinical symptoms without actually preventing the occurrence of varicella-zoster virus-related lesions such as the persistent pulmonary nodules reported here.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference14 articles.

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2. Arvin A. M. 1996. Varicella-zoster virus p. 2547-2585. In B. N. Fields D. M. Knipe P. M. Howley R. M. Chanock J. L. Melnick T. P. Monath and S. E. Straus (ed.) Fields virology 3rd ed. Lippincott-Raven Publishers Philadelphia Pa.

3. Cowl, C. T., U. B. Prakash, P. S. Mitchell, and M. R. Migden. 2000. Varicella-zoster virus detection by polymerase chain reaction using bronchoalveolar lavage specimens. Am. J. Respir. Crit. Care Med.162:753-754.

4. Gogos, C. A., H. P. Bassaris, and A. G. Vagenakis. 1992. Varicella pneumonia in adults. A review of pulmonary manifestations, risk factors and treatment. Respiration59:339-343.

5. Gray, G. C., L. A. Palinkas, and P. W. Kelley. 1990. Increasing incidence of varicella hospitalizations in United States Army and Navy personnel: are today's teenagers more susceptible? Should recruits be vaccinated? Pediatrics86:867-873.

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