Susceptibility of Nocardia asteroides to various antibiotics, including newer beta-lactams, trimethoprim-sulfamethoxazole, amikacin, and N-formimidoyl thienamycin

Author:

Gombert M E

Abstract

The susceptibility of 26 isolates of Nocardia asteroides to several antibiotics was determined by the agar dilution technique. Many currently available beta-lactam antibiotics were ineffective. Cefotaxime, cefmenoxime, and N-formimidoyl thienamycin were active against these strains, with 80% minimal inhibitory concentrations of 4, 4, and 2 micrograms/ml, respectively. Amikacin was the most effective agent tested.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference6 articles.

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4. Gordan M. A. 1980. Aerobic pathogenic actinomycetaceae p. 180-189. In E. H. Lennette A. Balows W. J. Hausler Jr. and J. P. Truant (ed.) Manual of clinical microbiology 3rd ed. American Society for Microbiology Washington D.C.

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