Spontaneous production of interleukin-2 and interleukin-3 by spleen cells from mice infected with mouse hepatitis virus type 4

Author:

Kyuwa S1,Yamaguchi K1,Hayami M1,Hilgers J1,Fujiwara K1

Affiliation:

1. Department of Animal Pathology, University of Tokyo, Japan.

Abstract

Spleen cells from mice, 4 to 60 days after infection with mouse hepatitis virus type 4, produced interleukin-2, as well as interleukin-3, in the absence of exogenous stimulants in vitro. This unique lymphokine production by mouse hepatitis virus type 4 infection was controlled by host genes.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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