Affiliation:
1. Graduate School of Agricultural Science, Hokkaido University, Sapporo, Japan
Abstract
One of the infection processes of
C. jejuni
, the invasion behavior of the bacteria in intestinal epithelial cells, was revealed, and a mathematical model for prediction of the cell-invading pathogen counts was developed for the purpose of providing part of a dose-response model for
C. jejuni
based on the infection mechanism. The developed predictive model showed a high accuracy of more than 97% and successfully described the
C. jejuni
invading counts. The bacterial invasion predictive model of this study will be essential for the development of a dose-response model for
C. jejuni
based on the infection mechanism.
Funder
Food Safety Commission, Japan
MEXT | Japan Society for the Promotion of Science
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
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