GENETIC HOMOLOGY BETWEEN ESCHERICHIA COLI K-12 AND SALMONELLA

Author:

Falkow Stanley12,Rownd R.12,Baron L. S.12

Affiliation:

1. Division of Communicable Disease and Immunology, Walter Reed Army Institute of Research, Washington, D.C.

2. The Department of Chemistry, Harvard University, Cambridge, Massachusetts

Abstract

Falkow, Stanley (Walter Reed Army Institute of Research, Washington, D.C.), Robert Rownd, and L. S. Baron . Genetic homology between Escherichia coli K-12 and Salmonella . J. Bacteriol. 84: 1303–1312. 1962.—Recombinant analysis and interrupted mating procedures, in conjunction with molecular hybridization experiments, demonstrated that the genetic homology between Escherichia and Salmonella is incomplete. The most likely explanation of this incomplete homology is imperfect pairing between the deoxyribonucleic acid molecules of the two species. Despite the inhomologies, there is ample evidence that the order and distance of the genetic characters on the Salmonella chromosome are identical to those of Escherichia .

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference25 articles.

1. Genetic recombination between genera of the Enterobacteriaceae. Proc. 21st;BARON L. S.;Ann. Biol. Colloq., p.,1960

2. BARON L. S. W. F. CAREY AND W. M. SPILMAN. 1958. Hybridization of Salmonella species by mating with Escherichia coli. Proc. Intern. Congr. Microbiol. 7th Stockholm p. 50.

3. Genetic recomibination between Escherichia coli and Salmonella typhimurium;BARON L. S.;Proc. Natl. Acad. Sci. U.,1959

4. Hybridization of Salmonella species by mating with Escherichia coli;BARON L. S.;Science,1959

5. Diploid heterozygous hybrids from matings between Escherichia coli and Salmonella typhosa;BARON L. S.;J. Exptl. Med.,1960

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