Biosynthesis of fusarochromanone and its monoacetyl derivative by Fusarium equiseti

Author:

Xie W P1,Mirocha C J1,Pawlosky R J1,Wen Y C1,Xu X G1

Affiliation:

1. Department of Plant Pathology, University of Minnesota, St. Paul 55108.

Abstract

One fluorescent compound previously named TDP-2 was isolated and purified from a rice culture of Fusarium equiseti (Alaska 2-2). Mass spectral and nuclear magnetic resonance data indicated that it is a C-3'-N-acetyl derivative of fusarochromanone, a newly discovered mycotoxin. Time course studies of synthesis of these two compounds on autoclaved rice and Czapek-Dox medium enriched with soybean peptone indicated that fusarochromanone was converted to TDP-2 in the cultures. A high concentration of peptone in the liquid medium may stimulate both fusarochromanone synthesis and its conversion to TDP-2.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference11 articles.

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2. Joffe A. Z. 1986. Effects of fusariotoxins in humans p. 287-291. In A. Z. Joffe (ed.) Fusarium species: their biology and toxicology. John Wiley & Sons Inc. Jerusalem.

3. A cartilage abnormality of broiler chickens;Laursen-Jones A. P.;Vet. Rec.,1970

4. Nutritional, genetic and morphological studies of an abnormal cartilage formation in young chicks;Leach R. M.;J. Nutr.,1965

5. TDP-1, a toxic component causing tibial dyschondroplasia in broiler chickens, and trichothecenes from Fusarium roseum 'graminearum;Lee Y.;Appl. Environ. Microbiol.,1985

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