Invasive Pneumococcal Disease and Influenza Activity in a Pediatric Population: Impact of PCV13 Vaccination in Epidemic and Nonepidemic Influenza Periods

Author:

Hernández Sergi1ORCID,Muñoz-Almagro Carmen2345,Ciruela Pilar12,Soldevila Núria26,Izquierdo Conchita1,Codina Maria Gemma7,Díaz Alvaro8,Moraga-Llop Fernando7,García-García Juan José234,Domínguez Ángela26

Affiliation:

1. Agència de Salut Pública de Catalunya, Generalitat de Catalunya, Barcelona, Spain

2. CIBER de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain

3. Malalties Prevenibles amb Vacunes, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain

4. Hospital Sant Joan de Déu Barcelona, Universitat de Barcelona, Barcelona, Spain

5. Departament de Medicina, Universitat Internacional de Catalunya, Barcelona, Spain

6. Departament de Medicina, Universitat de Barcelona, Barcelona, Spain

7. Hospital Universitari Vall d'Hebron, Barcelona, Spain

8. Hospital de Nens, Barcelona, Spain

Abstract

The objective of this study was to analyze the incidence, clinical presentation, and severity of invasive pneumococcal disease (IPD)-causing serotypes and the impact of the 13-valent pneumococcal conjugate vaccination during epidemic and nonepidemic influenza periods in Catalonia, Spain. This was a prospective study in persons aged <18 years diagnosed with IPD between 2012 and 2015 in three Catalan pediatric hospitals.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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