Genome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccine-Reference-Cited by-同舟云学术

Genome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccine

Published:2024-06-11 Issue:6 Volume:13 Page:
ISSN:2576-098X
Container-title:Microbiology Resource Announcements
language:en
Short-container-title:Microbiol Resour Announc

Author:

Mlingo Tendai A. M.¹²^ORCID,Beeton-Kempen Natasha³,Nthangeni M. Bethuel²,Theron Jacques¹,Mokoena Nobalanda B.²

Affiliation:

1. Department of Biochemistry, Genetics, and Microbiology, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South Africa

2. Research and Development-Virology, Onderstepoort Biological Products, Pretoria, South Africa

3. The Animal Health Group, TokaBio (PTY) LTD, Johannesburg, South Africa

Abstract

ABSTRACT Bluetongue disease in endemic areas is predominantly controlled through vaccination with live-attenuated vaccines. Sequencing of the original master seed viruses used in the production of Onderstepoort Biological Products vaccine was conducted. Nucleotide identities of 82.97%–100% were obtained for all sequences when compared to South African reference strains.

Publisher

American Society for Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mra.00223-24

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