Complete Genome Sequence of the Collinolactone Producer Streptomyces sp. Strain Gö40/10

Author:

Sterndorff Eva B.1,Jørgensen Tue S.1ORCID,Garzón Jaime Felipe Guerrero1,Schmid Julian2,Grond Stephanie2,Weber Tilmann1ORCID

Affiliation:

1. The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, Denmark

2. Institut für Organische Chemie, Eberhard Karls Universität Tübingen, Tübingen, Germany

Abstract

The actinomycete Streptomyces sp. strain Gö40/10 has the potential to produce a range of secondary metabolites, one of which is collinolactone, a compound with neuroprotective properties and potential for pharmaceutical applications. The genome was sequenced with Oxford Nanopore Technologies MinION and Illumina MiSeq systems and consists of a single 9,635,564-nucleotide linear chromosome.

Funder

Novo Nordisk Fonden

Publisher

American Society for Microbiology

Subject

Genetics,Immunology and Microbiology (miscellaneous),Molecular Biology

Reference15 articles.

1. Schuhmann T. 2005. Untersuchungen zur Biosynthese und Aktivität ausgewählter Plecomakrolide sowie chemisches Screening von Actinomyceten. Dr. rer. nat. dissertation. Georg August University of Göttingen, Göttingen, Germany.

2. Cineromycins, .GAMMA.-Butyrolactones and Ansamycins by Analysis of the Secondary Metabolite Pattern Created by a Single Strain of Strepomycest.

3. The Structure of Cyclodecatriene Collinolactone, its Biosynthesis, and Semisynthetic Analogues: Effects of Monoastral Phenotype and Protection from Intracellular Oxidative Stress

4. Kieser T, Bibb MJ, Buttner MJ, Chater K. 2000. Practical Streptomyces genetics. John Innes Foundation, Norwich, United Kingdom.

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