Systematic Genetic Interaction Analysis Identifies a Transcription Factor Circuit Required for Oropharyngeal Candidiasis-Reference-Cited by-同舟云学术

Systematic Genetic Interaction Analysis Identifies a Transcription Factor Circuit Required for Oropharyngeal Candidiasis

Published:2022-02-22 Issue:1 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Solis Norma V.¹,Wakade Rohan S.²,Glazier Virginia E.³,Ollinger Tomye L.²,Wellington Melanie²,Mitchell Aaron P.⁴^ORCID,Filler Scott G.¹⁵,Krysan Damian J.²⁶^ORCID

Affiliation:

1. Division of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA

2. Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA

3. Department of Biology, Niagara University, Niagara Falls, New York, USA

4. Department of Microbiology, University of Georgia, Athens, Georgia, USA

5. Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA

6. Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA

Abstract

The pathology of oral candidiasis has features of biofilm formation, a well-studied process in vitro . Based on that analogy, we hypothesized that the network of transcription factors that regulates in vitro biofilm formation has similarities and differences during oral infection.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.03447-21

Reference36 articles.

1. Invasive candidiasis

2. Oral Candidiasis: A Disease of Opportunity

3. Oral candidiasis