Targeting of Mammalian Glycans Enhances Phage Predation in the Gastrointestinal Tract-Reference-Cited by-同舟云学术

Targeting of Mammalian Glycans Enhances Phage Predation in the Gastrointestinal Tract

Published:2021-02-23 Issue:1 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Green Sabrina I.¹,Gu Liu Carmen¹^ORCID,Yu Xue¹,Gibson Shelley²,Salmen Wilhem¹,Rajan Anubama¹,Carter Hannah E.¹,Clark Justin R.¹,Song Xuezheng³,Ramig Robert F.¹,Trautner Barbara W.⁴⁵,Kaplan Heidi B.⁶,Maresso Anthony W.¹

Affiliation:

1. Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA

2. Department of Human Genetics, Baylor College of Medicine, Houston, Texas, USA

3. Department of Biochemistry, Emory Comprehensive Glycomics Core, Emory University School of Medicine, Atlanta, Georgia, USA

4. Michael E. Debakey Veterans Affairs Medical Center, Houston, Texas, USA

5. Department of Medicine, Baylor College of Medicine, Houston, Texas, USA

6. Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA

Abstract

Invasive pathobionts or microbes capable of causing disease can reside deep within the mucosal epithelium of our gastrointestinal tract. Targeted effective antibacterial therapies are needed to combat these disease-causing organisms, many of which may be multidrug resistant.

Funder

Roderick MacDonald Research Fund

Mike Hogg Foundation

Baylor College of Medicine Seed Funds

U.S. Department of Veterans Affairs

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.03474-20

Reference90 articles.