Variation in Host Resistance to Blastomyces dermatitidis: Potential Use of Genetic Reference Panels and Advances in Immunophenotyping of Diverse Mouse Strains-Reference-Cited by-同舟云学术

Variation in Host Resistance to Blastomyces dermatitidis: Potential Use of Genetic Reference Panels and Advances in Immunophenotyping of Diverse Mouse Strains

Published:2022-02-22 Issue:1 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Kohn Elaine M.¹,Taira Cleison¹,Dobson Hanah¹,Dias Lucas Dos Santos¹,Okaa Uju¹,Wiesner Darin L.¹,Wüthrich Marcel¹,Klein Bruce S.¹²³

Affiliation:

1. Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, University of Wisconsin—Madison, Madison, Wisconsin, USA

2. Department of Internal Medicine, University of Wisconsin School of Medicine and Public Health, University of Wisconsin—Madison, Madison, Wisconsin, USA

3. Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, University of Wisconsin—Madison, Madison, Wisconsin, USA

Abstract

Host genetic variation significantly impacts vulnerability to infectious diseases. While host variation in susceptibility to fungal infection with dimorphic fungi has long been recognized, genes that underpin this variation are poorly understood.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.03400-21

Reference39 articles.

1. Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database

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4. On the subspecific origin of the laboratory mouse

5. Common Heritable Immunological Variations Revealed in Genetically Diverse Inbred Mouse Strains of the Collaborative Cross

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