Triclosan Tolerance Is Driven by a Conserved Mechanism in Diverse Pseudomonas Species-Reference-Cited by-同舟云学术

Triclosan Tolerance Is Driven by a Conserved Mechanism in Diverse Pseudomonas Species

Published:2021-03-11 Issue:7 Volume:87 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

McFarland Alexander G.¹,Bertucci Hanna K.¹,Littman Erica¹,Shen Jiaxian¹,Huttenhower Curtis²³⁴,Hartmann Erica M.¹^ORCID

Affiliation:

1. Department of Civil and Environmental Engineering, Northwestern University, Evanston, Illinois, USA

2. Harvard Chan Microbiome in Public Health Center, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA

3. Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA

4. Infectious Disease and Microbiome Program, Broad Institute, Cambridge, Massachusetts, USA

Abstract

Closely related species are typically assumed to demonstrate similar phenotypes driven by underlying conserved genotypes. When monitoring for the effect of antimicrobials on the types of species that may be selected for, this assumption may prove to be incorrect, and identification of additional genetic markers may be necessary.

Funder

Northwestern University undergraduate summer research grant

Northwestern University undergraduate fall research grant

HHS | Centers for Disease Control and Prevention

Alfred P. Sloan Foundation

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.02924-20

Reference74 articles.