Use of Murine Norovirus as a Surrogate To Evaluate Resistance of Human Norovirus to Disinfectants

Author:

Belliot Gaël1,Lavaux Amandine1,Souihel Donya1,Agnello Davide1,Pothier Pierre1

Affiliation:

1. Laboratoire de Virologie, Centre National de Référence des Virus Entériques, Centre Hospitalier Universitaire de Dijon, 7 boulevard Jeanne d'Arc, 21079 Dijon Cedex, France

Abstract

ABSTRACT Murine norovirus (MNV) was used as a surrogate to study resistance of human norovirus to disinfectants used in hospitals. MNV was sensitive to alcohol, alcohol hand rubs, bleach, and povidone iodine-based disinfectant. Real-time reverse transcription-PCR results indicated that the presence of viral RNA did not correlate with the presence of infectious virus.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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