Lack of ciprofloxacin ototoxicity after repeated ototopical application

Author:

Claes J1,Govaerts P J1,Van de Heyning P H1,Peeters S1

Affiliation:

1. Department of Otorhinolaryngology, University of Antwerp, Belgium.

Abstract

The possible side effects of ototopically applied ciprofloxacin on inner ear function were investigated. The hearing function of pigmented guinea pigs was evaluated by daily frequency-specific evoked response audiometry after repeated application of the drug to both ears. Ciprofloxacin appeared to have no statistically significant effect on the hearing thresholds of the experimental animals.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference8 articles.

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4. Nomura Y. 1984. Otological significance of the round window.

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