Biotransformation of aflatoxin B1 and its conjugated metabolites by rat gastrointestinal microfloras-Reference-Cited by-同舟云学术

Biotransformation of aflatoxin B1 and its conjugated metabolites by rat gastrointestinal microfloras

Published:1981-02 Issue:2 Volume:41 Page:549-551
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Wei C,Macy J M,Hsieh D P

Abstract

Rat cecal microflora from high- and low-fiber-fed animals hydrolyzed aflatoxin conjugates to metabolites indistinguishable from aflatoxin B1 and aflatoxin P1, but aflatoxicol was not a transformation product.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.41.2.549-551.1981

Reference18 articles.

1. Epidemiology of cancer of the colon and rectum;Burkitt D. P.;Cancer,1971

2. Conversion of aflatoxin B, to isomeric hydroxy compounds by Rhizopus app;Cole R. J.;J. Agric. Food Chem.,1972

3. Maintenance of cytochrome P-450 and metabolism of aflatoxin B, in primary hepatocyte cultures;Decad G. M.;Biochem. Biophys. Res. Commun.,1977

4. Detroy R. W. and C. W. Hesseltine. 1969. Transfor-NOTES 551

5. Aflatoxicol: structure of a new transformation product of aflatoxin B;Detroy R. W.;Can. J. Biochem.,1970

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Acute aflatoxin B1-induced gastro-duodenal and hepatic oxidative damage is preceded by time-dependent hyperlactatemia in rats;Mycotoxin Research;2020-09-21

2. Bioactivation of cysteine conjugates of 1-nitropyrene oxides by cysteine conjugate beta-lyase purified from Peptostreptococcus magnus;Applied and Environmental Microbiology;1995-11

3. Biological activities of the intestinal microflora in mice treated with antibiotics or untreated and the effects of the microflora on absorption and metabolic activation of orally administered glutathione conjugates of K-region epoxides of 1-nitropyrene;Carcinogenesis;1993

4. Deconjugation of Biliary Metabolites by Microfloral β-glucuronidases, Sulphatases and Cysteine Conjugate β-lyases and their Subsequent Enterohepatic Circulation;Role of the Gut Flora in Toxicity and Cancer;1988

5. Effect of butylated hydroxytoluene pretreatment on the excretion, tissue distribution and DNA binding of [14C]aflatoxin B1 in the rat;Food and Chemical Toxicology;1985-06